: Pain Physician. 2008 Mar-Apr;11(2):133-6.
Prevalence of complex regional pain syndrome in a cohort of multiple sclerosis patients.
Drexel University College of Medicine, Department of Neurology, Philadelphia, PA, USA.
BACKGROUND: More than 50% of multiple sclerosis patients experience chronic pain syndrome. We set out to determine the specific type of chronic pain that was seen in our multiple sclerosis patients.
METHODS: Patients with multiple sclerosis were catalogued between January 2002 and April 2006 and identified by a search of the database. Only MS patients that met the 2005 revised McDonald criteria were included. RESULTS: We determined the prevalence rate of complex regional pain syndrome in a cohort of multiple sclerosis patients. In our sample of 205 multiple sclerosis patients, the prevalence of complex regional pain syndrome was 4 cases per 205 compared to an expected age and sex-adjusted total prevalence of 0.078 cases per 205 (p <>
CONCLUSION: This study suggests that multiple sclerosis patients are at a higher risk of developing complex regional pain syndrome than the general population.